Comparative effect of butyric acid alone and with endogenous quorum quencher bacteria on biochemical parameters of Acanthopagrus arabicus

Salehipour Bavarsad , Simak; Mohammadian , Takavar; Kochanian , Preeta; Yavari , Vahid; Torfi mozan zadeh , Mansour

doi:10.22034/AER.1.1.75

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Volume 1, Issue 3 (10-2025)

Journalaer 2025, 1(3): 75-86

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Comparative effect of butyric acid alone and with endogenous quorum quencher bacteria on biochemical parameters of Acanthopagrus arabicus

Simak Salehipour Bavarsad ^*

, Takavar Mohammadian

, Preeta Kochanian

, Vahid Yavari

, Mansour Torfi mozan zadeh

Abstract: (1077 Views)

Introduction: Considering the significance of Acanthopagrus arabicus in Iran, characterized by its carnivorous nature and robust digestive system adapted for high-protein diets, there culture a necessity for the use of dietary supplements such as acidifier probiotics. This study was undertaken to investigate the impact of administering quorum quencher probiotics independently and in conjunction with the acidifier butyric acid on the alterations in biochemical parameters in A. arabicus.
Materials & Methods: A total of 360 fish fry, with an average weight of 15±3.2 gr, were randomly assigned to eight experimental treatments, each repeated three times. Over a period of 60 days, all fish groups were fed with the experimental diet. The treatments included: 1. Treatment A: Food with 0.5% butyric acid per Kg. 2. Treatment B: Bacillus cereus with quorum quenching properties (cfu g-1 10⁸) per kg of ration. 3. Treatment C: B. thuringiensis with quorum quenching properties (10⁸ cfu g-1) per Kg of diet (B). 4. Treatment D: B. cereus and B. thuringiensis with quorum quenching properties (10⁸ cfu g-1) per Kg of diet (C). 5. Treatment E: B. cereus with quorum quenching property (10⁸ cfu g-1) along with 0.5% butyric acid per Kg of food. 6. Treatment F: B. thuringiensis with quorum quenching properties (10⁸ cfu g-1) along with 0.5% butyric acid per Kg of food. 7. Treatment G: B. cereus and B. thuringiensis with quorum quenching properties (108 cfu g-1) along with 0.5% butyric acid per Kg of food. 8. Control Treatment H: Food without acidifying probiotics. The control group received daily commercial food with 42% protein, including 100% fish meal.
Results: The consumption of diets containing a combination of B1 and B2 probiotics with butyric acid (Treatment G) and the group fed with the combination of probiotic B1 with butyric acid (Treatment F) resulted in a significant increase in glucose, triglyceride, cholesterol, and creatine phosphokinase in fish serum. Additionally, protein levels in fish serum increased, particularly in treatments containing Bacillus B1, Bacillus B2, and butyric acid alone, and the combination of both probiotics (Treatment D) compared to the control group. A substantial increase in albumin was observed in groups containing the combination of B1 and B2 bacilli along with butyric acid (Treatment D) and groups B and E. Moreover, the calcium content in the blood serum of fish fed with probiotic compound B2 (Treatment C) was higher than other treatments, especially the control group (H).
Conclusion: In summary, the combination of probiotics with butyric acid, along with the combination of B1 and B2 probiotics, has led to significant improvements in glucose, protein, albumin, cholesterol, triglyceride, calcium, and creatine phosphokinase enzyme activity.

Keywords: Probiotics, Quorum quencher bacteria, Butyric acid, Acanthopagrus arabicus, Biochemical parameters

Full-Text [PDF 1053 kb] (411 Downloads)

Type of Study: Research | Subject: Special
Received: 2025/09/6 | Accepted: 2025/10/2 | Published: 2025/10/2

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Salehipour Bavarsad S, Mohammadian T, Kochanian P, Yavari V, Torfi mozan zadeh M. Comparative effect of butyric acid alone and with endogenous quorum quencher bacteria on biochemical parameters of Acanthopagrus arabicus. Journalaer 2025; 1 (3) :75-86
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